St. Anthony de Padua Parish was established by the faith of the Shrine Workers of St. Anthony. Located in Cementville, the missionary church was named in honor of the patron of San Antonio.
In 1925, Fr. Peter Baque wanted to form a congregation committed to serving the community. a small chapel was built in 1927 by the pecan shellers, Cementville workers, and others.
During the next decade, the congregation grew in number and spirituality. Pilgrims came to workship at the site, a school was opened, and the Missionary Servants of St. Anthony were founded to teach and serve the community.